Biomarkers & Clocks
Epigenetic Age vs Chronological Age in Cohort Studies
Biological aging, not calendar years, predicts disease and decline.
Priya Venkataraman
· 9 min read
Longevity Science Review — Page 3
Autophagy Decline and Protein Aggregation in Aging
Blocking this recycling system triggers a destructive loop that aging cells can't escape.
Priya Venkataraman
Telomere Attrition and Healthspan Outcomes
Shorter telomeres predict faster aging and earlier disease, but lifestyle factors can slow the loss.
Marcus Osei-Bonsu
Epigenetic Clocks and Drift Explained
Biological age measures how fast aging is happening now, not how old you are on paper.
Priya Venkataraman
mTOR Signaling and Nutrient Sensing in Aging
Chronic activation of this nutrient sensor disrupts cellular cleanup and accelerates aging.
Marcus Osei-Bonsu
NAD+ Decline Mechanisms Across the Lifespan
Three separate mechanisms drive NAD+ decline, each worsening the others with age.
Teodora Halász
Intercellular Communication Breakdown in Aging Tissues
Cells stop talking clearly to each other as they age, turning local damage into body-wide decline.
Priya Venkataraman
Inflammaging and Chronic Low-Grade Inflammation
Five molecular pathways drive age-related inflammation, but diet offers the strongest brake.
Priya Venkataraman